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	<title>Sepientia &#187; gene</title>
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	<link>http://sepientia.com</link>
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		<title>British scientists have uncovered the gene that regulates our heartbeat.</title>
		<link>http://sepientia.com/2010/01/british-scientists-have-uncovered-the-gene-that-regulates-our-heartbeat/</link>
		<comments>http://sepientia.com/2010/01/british-scientists-have-uncovered-the-gene-that-regulates-our-heartbeat/#comments</comments>
		<pubDate>Fri, 29 Jan 2010 15:51:59 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Medicine]]></category>
		<category><![CDATA[Science]]></category>
		<category><![CDATA[gene]]></category>
		<category><![CDATA[heartbeat]]></category>
		<category><![CDATA[scientists]]></category>

		<guid isPermaLink="false">http://sepientia.com/?p=1206</guid>
		<description><![CDATA[The discovery of the &#8220;pacemaker gene&#8221; could lead to new drug treatments to avoid heart attacks and disease, say experts.
A person&#8217;s heartbeat is controlled by electrical signals, which start in one central place &#8211; the heart&#8217;s pacemaker &#8211; and travel around the heart muscle.
And now, a team at Imperial College London have found the gene [...]]]></description>
			<content:encoded><![CDATA[<p><img class="alignleft size-medium wp-image-1205" title="human-heart-01" src="http://sepientia.com/wp-content/uploads/2010/01/human-heart-01-222x300.jpg" alt="" width="222" height="300" />The discovery of the &#8220;pacemaker gene&#8221; could lead to new drug treatments to avoid heart attacks and disease, say experts.</p>
<p>A person&#8217;s heartbeat is controlled by electrical signals, which start in one central place &#8211; the heart&#8217;s pacemaker &#8211; and travel around the heart muscle.</p>
<p>And now, a team at Imperial College London have found the gene that controls those electrical signals and thus the rhythm of the heart.</p>
<p>The researchers claimed that the damage or mutations to the gene &#8211; known as SCN10A &#8211; increase the risk of heart disease.</p>
<p>The researchers believe that the finding could help them to understand how the body&#8217;s heartbeat is controlled and could ultimately help them come up with new treatments for heart rhythm disturbances.</p>
<p><span id="more-1206"></span>It is also hoped that studying different variations of the gene in different people will help doctors discover why some people are more susceptible to heart trouble than others.</p>
<p>&#8220;Genetic variation is like the two sides of a coin. One side is associated with increased risk, the other with decreased risk. We have identified a gene that influences heart rhythm, and people with different variants of the gene will have increased or decreased risks of developing heart rhythm problems,&#8221; the Telegraph quoted Dr John Chambers, lead author of the study as saying.</p>
<p>In the study, the researchers analysed the genetic make-up of almost 20,000 people to look for genetic factors influencing the heartbeat.</p>
<p>They studied the electrocardiogram (ECG, a recording of the heartbeat) of each person, and measured the time taken for electrical signals to travel to different parts of the heart.</p>
<p>They found that variation in the gene SCN10A was linked with slow and irregular heart rhythms, including risk of ventricular fibrillation.</p>
<p>ANI</p>
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